Senior Research Associate, Immuno-oncology

Pionyr Immunotherapeutics is a growing South San Francisco-based clinical stage immuno-oncology company focused on novel approaches to cancer immunotherapy. We are looking for a highly motivated and dedicated candidate for a full-time Senior Research Associate position in our research group. The successful candidate will be an integral member of the in vitro pharmacology team and will play a critical role in advancing our early-stage programs into the clinic by generating experimental data that inform key program decisions and enable IND preparation.

Specific Responsibilities

  • Performs hands-on research activities to support the design and implementation of immune cell-based assays to interrogate myeloid cell target biology, therapeutic mechanisms of action, and inform lead optimization. Specific techniques routinely used include isolation of primary cells, immunophenotyping by multi-parameter flow cytometry, and immune functional assays, such as antigen presentation, phagocytosis, cell signaling reporter assays, and ELISA.
  • Troubleshoots and optimizes assays through surveying the literature for alternative or novel approaches
  • Organizes, analyzes and interprets data with minimal supervision, and presents findings in team meetings


Requirements

  • B.Sc. or M.Sc. in Immunology, Cancer Biology, or a related field, with a minimum of 5 years of relevant experience in an industrial or academic lab setting
  • Hands-on experience in immuno-oncology assays; experience with myeloid cells is a plus
  • Ex vivo culture of primary leukocytes and development of immune cell-based assays, including phagocytosis, antigen presentation, and T cell activation
  • Isolation and immunophenotyping of mouse and/or human immune cells
  • Proficiency in multi-color flow cytometry and FlowJo software
  • Experience with immunological (ELISA, MSD) and molecular biology (RT-PCR, Western blot) techniques and data analysis
  • Strong verbal and writing skills for data documentation, study reporting, and communication of progress to team members and management
  • Passion about scientific discovery and capability to critically analyze and interpret data with minimal supervision
  • Good communication skills and proven ability to collaborate in a team setting
  • Pionyr Immunotherapeutics Inc. offers competitive salaries, participation in company stock-incentive plans and benefits packages, in addition to a dynamic, collaborative and academic-driven science environment.

How to Apply

Pionyr Immunotherapeutics Inc. offers competitive salaries, participation in company stock-incentive plans and benefits packages, in addition to a dynamic academic-driven science environment. If you would like to be part of a team-based and collaborative company developing innovative immuno-oncology therapeutics, please send your resume to careers@pionyrtx.com.

Thank you for your interest in Pionyr Immunotherapeutics. We are an equal opportunity employer.